Print Share Email Send Email Your Name (required) Example: John Doe This field is required. Email Address (required) Error: Please enter a valid sender email address. Example: jdoe@example.com CC Me This field is required. Please enter a valid email address. Recipient Email Address(es) (required - use a semicolon to separate multiple addresses) Separate multiple email address with semi-colons (up to 5). This field is required. Please enter a valid email address. One or more of your email addresses are invalid. Please review before submitting. Subject Subject for your email. Message (Maximum characters: 1,000) Thank you! Your email has been sent to: The recipient(s) will receive an email message that includes a link to the selected article. Recipients may need to check their spam filters or confirm that the address is safe. Return to: Send Another Email An error has occurred sending your email(s). Please try again later or contact an administrator at OnlineCustomer_Service@email.mheducation.com. Return to: Twitter Facebook Linkedin Reddit Get Citation Citation Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. Please consult the latest official manual style if you have any questions regarding the format accuracy. AMA Citation Vernon H. Vernon H Vernon, Hilary. CoEnzyme Q10 deficiency leads to downstream disruption of sulfide metabolism. OMMBID Blog, 9 December 2016. McGraw Hill, 2016. OMMBID. https://ommbid.mhmedical.com/updatesContent.aspx?gbosid=324365§ionid=147640697APA Citation Vernon H. Vernon H Vernon, Hilary. (2016). Coenzyme q10 deficiency leads to downstream disruption of sulfide metabolism. (2016). Ommbid blog. McGraw Hill. https://ommbid.mhmedical.com/updatesContent.aspx?gbosid=324365§ionid=147640697.MLA Citation Vernon H. Vernon H Vernon, Hilary. "CoEnzyme Q10 deficiency leads to downstream disruption of sulfide metabolism." OMMBID Blog McGraw Hill, 2016, https://ommbid.mhmedical.com/updatesContent.aspx?gbosid=324365§ionid=147640697. Download citation file: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager Mendeley © Copyright Tools Clip Full Chapter Figures Only Tables Only Videos Only Supplementary Content CoEnzyme Q10 deficiency leads to downstream disruption of sulfide metabolism by Hilary Vernon, MD PhD, Assistant Professor of Genetic Medicine, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University Listen + +Luna-Sanchez et al (EMBO Molecular Medicine, November 2016, pii: e201606345. doi: 10.15252/emmm.201606345) recently published an article in which they described downstream effects of CoEnzyme Q10 deficiency in both a fibroblast model and two mouse models of primary CoQ10 deficiency. This group uncovered alterations in thiol metabolism, and subsequent changes in the biosynthesis glutamate, serotonin and catecholamine metabolism. +Effects on sulfur metabolic pathways are increasingly implicated in models of mitochondrial disease, and represent an important direction for both research and potential therapeutic intervention. +Hilary Vernon, MD PhD