RT Book, Section
A1 Sabbagh, Yves
A1 Tenenhouse, Harriet S.
A1 Econs, Michael J.
A1 Auricchio, Alberto
A2 Valle, David L.
A2 Antonarakis, Stylianos
A2 Ballabio, Andrea
A2 Beaudet, Arthur L.
A2 Mitchell, Grant A.
SR Print(0)
ID 1181473691
T1 Mendelian Hypophosphatemias
T2 The Online Metabolic and Molecular Bases of Inherited Disease
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071459969
LK ommbid.mhmedical.com/content.aspx?aid=1181473691
RD 2024/04/16
AB Inorganic  phosphate  is  an  essential  nutrient  in  terms  of  both  cell  function  and  skeletal  mineralization.  It  is  required  for  glycolysis,  gluconeogenesis,  and  energy  metabolism,  as  well  as  for  the  synthesis  of  DNA,  RNA,  membrane  phospholipids,  and  a  variety  of  phosphorylated  intermediates.  In  addition,  the  phosphorylation  of  cellular  proteins  is  a  major  mechanism  by  which  cell  function  is  controlled.  Intracellular  regulatory  roles  for  the  inorganic  phosphate  anion  involve  such  diverse  functions  as  control  of  aerobic  metabolism,  control  of  the  O2  dissociation  curve  of  hemoglobin  in  the  intact  red  blood  cell,  and  regulation  of  cellular  calcium  metabolism.