RT Book, Section A1 Tollefsen, Douglas M. A2 Valle, David L. A2 Antonarakis, Stylianos A2 Ballabio, Andrea A2 Beaudet, Arthur L. A2 Mitchell, Grant A. SR Print(0) ID 1181455855 T1 Antithrombin Deficiency T2 The Online Metabolic and Molecular Bases of Inherited Disease YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071459969 LK ommbid.mhmedical.com/content.aspx?aid=1181455855 RD 2024/10/03 AB This update summarizes recent advances in the structure, mechanism, and physiology of antithrombin (gene symbol SERPINC1) and heparin cofactor II (gene symbol SERPIND1, alias HCF2). Current recommendations for treatment of inherited and acquired antithrombin deficiency are reviewed elsewhere.1 A database of antithrombin mutations is available online (http://www1.imperial.ac.uk/departmentofmedicine/divisions/experimentalmedicine/haematology/coag/antithrombin/).