TY - CHAP M1 - Book, Section TI - Antithrombin Deficiency A1 - Tollefsen, Douglas M. A2 - Valle, David L. A2 - Antonarakis, Stylianos A2 - Ballabio, Andrea A2 - Beaudet, Arthur L. A2 - Mitchell, Grant A. PY - 2019 T2 - The Online Metabolic and Molecular Bases of Inherited Disease AB - This update summarizes recent advances in the structure, mechanism, and physiology of antithrombin (gene symbol SERPINC1) and heparin cofactor II (gene symbol SERPIND1, alias HCF2). Current recommendations for treatment of inherited and acquired antithrombin deficiency are reviewed elsewhere.1 A database of antithrombin mutations is available online (http://www1.imperial.ac.uk/departmentofmedicine/divisions/experimentalmedicine/haematology/coag/antithrombin/). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - ommbid.mhmedical.com/content.aspx?aid=1181455855 ER -