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Abstract

Nothing in biology makes sense except in the light of evolution and nothing in medicine makes sense except in the light of biology. The essay proposes that medicine is a science of the individual and when the experiences that undermine health are ameliorated, the continuing diseases in the population, in individuals, are increasingly likely to have biological explanations: some are Mendelian but most are multifactorial and complex. How we respond to this transition will influence education and practice.

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